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UNDERSTANDING
GLP-1 WEIGHT LOSS

An overview of GLP-1–based therapies for medical weight management

WHAT ARE GLP-1 MEDICATIONS

GLP-1 receptor agonists are a class of medications originally developed to support blood sugar regulation in people with type 2 diabetes. Some medications in this class have since received FDA approval for chronic weight management in individuals with obesity or certain weight-related conditions.

These treatments may be considered when lifestyle changes alone have not resulted in sufficient or sustained weight loss and when clinically appropriate, as determined by a healthcare provider.

HOW GLP-1 MEDICATIONS 
SUPPORT WEIGHT LOSS

GLP-1 and dual-action GIP/GLP-1 medications support weight loss by decreasing appetite, slowing gastric emptying, improving insulin sensitivity, and promoting better portion control while reducing food cravings. For eligible individuals, these combined effects can lead to an average weight loss of 10–20% or more when paired with a healthy lifestyle.

WHO MAY QUALIFY

GLP-1 therapy may be appropriate for individuals with a body mass index (BMI) of 30 or higher, or for those with a BMI of 27 or higher who also have a weight-related condition such as obstructive sleep apnea, high blood pressure, or type 2 diabetes.

At TrimMedix, every treatment plan is personalized. A licensed healthcare provider will evaluate your medical history, health goals, and overall profile to determine the safest and most effective approach for your needs.

INSURANCE AND
TREATMENT ACCESS

TrimMedix provides provider-led medical weight management and care coordination services. Clinical fees apply and cover services such as insurance navigation and prior authorization support for FDA-approved GLP-1 medications when prescribed, including coverage reviews, appeals, and coordination with manufacturer-sponsored support programs, when available.

If FDA-approved options are not accessible or medically appropriate, your provider may recommend a personalized treatment plan based on your medical history and goals. This plan may include other injectable therapies, prescription appetite suppressants, hormone optimization, functional medicine support, or compounded options.

SAFETY AND SIDE EFFECTS

As with any prescription medication, GLP-1-based therapies may carry potential risks and side effects. The most commonly reported include nausea, vomiting, diarrhea, constipation, and fatigue—particularly during the initial dose escalation phase. More serious but less common risks include pancreatitis, gallbladder disease, kidney problems, and thyroid tumors, including medullary thyroid carcinoma (MTC).

GLP-1 medications are not recommended for individuals with a personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2).

At TrimMedix, all risks and benefits are reviewed in detail with a licensed provider before starting treatment. Ongoing monitoring is provided to ensure your safety and comfort throughout your care.

GET A FAST QUOTE FOR
INJECTION THERAPY FOR WEIGHT LOSS

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How Much Weight Would You Like To Lose?
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GLP-1 medications have been featured in: 

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Note: Compounded medications are not FDA-approved and are not equivalent to FDA-approved brand-name medications. They may be prescribed when an FDA-approved option is unavailable or medically unsuitable for a specific patient.

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